Ensuring the compatibility of medical devices or implants with the human body is an important design objective for medical products.

Simulation tools can efficiently assist to achieve this objective. Beside the rigorous reduction of in-vitro-tests, they offer advantages with regard to a detailed insight into the three dimensional processes in the particular device. Compared to the black-box approach of many experimental investigations, the causes of a possible biological incompatibility can be located precisely. Thus, a much more target-oriented optimisation of medical devices or implants can be achieved. With this in turn, the number of necessary cycles in the development process and hence the overall development time can be considerably reduced.

Through intensive, internationally recognised research in the area of biocompatibility assessment combined with many practical validations, ASD owns a comprehensive repertoire of simulation-based analysis tools.

Essentially, these comprehend tools for analysing

mechanical cell damage (e.g. haemolysis of red blood cells)

thermal cell damage

flow-induced platelet activation

device-induced thrombosis (white and red thrombus formation)

bone remodelling due to loads from implants

thermal bone damage (for example caused bei frictional forces during insertion of implants)

With our services, the concurrent prediction and assessment of both the technical functionality and the biological compatibility can be performed. Using these services, our customers can develop innovative medical devices and artificial organs with an outstanding biocompatibiblity.

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