Research project "3D Pivot"


Kick-off-Meeting in Timisoara/Rumänien in August 2018


The aim of the recently launched collaborative project "3D Pivot - 3D bio-Printing for Insulin-producing Vascularized Organs following Tumor resection" is the further development of technology for sustainable bioprinting and organ replacement based on 3D bioprinting. It is intended to provide a viable implantable pancreas first in patients with pancreatic cancer who undergo a partial or complete pancreatectomy. Once the technology has proven to be functional, it can also be transmitted to patients with diabetes.


The ASD is responsible for the development of a simulation-based method to optimize the perfusion of 3D printed cell systems. This modeling software for individual blood vessel and perfusion simulation aims to ensure viability and sufficiently small microcirculation at each tissue site in the printed cell composite, as the lack of adequate perfusion and thus nutrient transport by diffusion alone results in cell death. The novel software for the generation of 3D tissue models and the development of a special bioprinter for beta-cell organoids with integrated incubator as well as rationalization of the cell acquisition and proliferation process are intended to successfully lay the foundations for the bioprinting of an artificial pancreas.

More information can be found here.